TCR name | TCR mutation | TCR mutation chain | MHC allele | MHC mutation | MHC mutation chain | Peptide | Peptide mutation | KD (μM) | ΔG (kcal mol-1) | PDB | Template PDB | PMID |
---|---|---|---|---|---|---|---|---|---|---|---|---|
D2 | WT | nan |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 15.8+/-0.4 | -6.55 | 4OZG | 24777060 | |
D2 | N36A | A |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 14.0+/-.05 | -6.62 | 4OZG | 24777060 | |
D2 | Y38A | A |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | >300 | \N | 4OZG | 24777060 | |
D2 | Y40F | A |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | >300 | \N | 4OZG | 24777060 | |
D2 | L57A | A |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 116.8+/-14.5 | -5.36 | 4OZG | 24777060 | |
D2 | Y55F | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 5.3+/-0.4 | -7.2 | 4OZG | 24777060 | |
D2 | Q57A | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 69.5+/-5.5 | -5.67 | 4OZG | 24777060 | |
D2 | N63A | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 13.1+/-0.6 | -6.66 | 4OZG | 24777060 | |
D2 | F108A | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 178.3+/-21.2 | -5.11 | 4OZG | 24777060 | |
D2 | R109A | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | >300 | \N | 4OZG | 24777060 | |
D2 | F110A | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 70.2+/-4.2 | -5.67 | 4OZG | 24777060 | |
D2 | D114A | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 256.2+/-59.9 | -4.9 | 4OZG | 24777060 | |
D2 | Y117F | B |
HLA-DQA1*05:01 HLA-DQB1*02:01 | WT | nan | PQPELPYPQ | WT | 38.9+/-1.5 | -6.02 | 4OZG | 24777060 |