TCR name | TCR mutation | TCR mutation chain | MHC allele | MHC mutation | MHC mutation chain | Peptide | Peptide mutation | KD (μM) | ΔG (kcal mol-1) | PDB | Template PDB | PMID |
---|---|---|---|---|---|---|---|---|---|---|---|---|
SP3.4 | WT | nan |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 11.4+/-.06 | -6.74 | 4GG6 | 23063329 | |
SP3.4 | D108S | A |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | >200 | \N | 4GG6 | 23063329 | |
SP3.4 | R110K | A |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | >200 | \N | 4GG6 | 23063329 | |
SP3.4 | R110A | A |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | >200 | \N | 4GG6 | 23063329 | |
SP3.4 | L37A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 91.2+/-8.3 | -5.51 | 4GG6 | 23063329 | |
SP3.4 | Y57F | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 14.8+/-0.6 | -6.59 | 4GG6 | 23063329 | |
SP3.4 | Y57A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | >200 | \N | 4GG6 | 23063329 | |
SP3.4 | R66A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 2.3+/-0.1 | -7.69 | 4GG6 | 23063329 | |
SP3.4 | V108A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 33.3+/-1.5 | -6.11 | 4GG6 | 23063329 | |
SP3.4 | A109G | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 9.8+/-0.3 | -6.83 | 4GG6 | 23063329 | |
SP3.4 | V110A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 14.3+/-0.7 | -6.61 | 4GG6 | 23063329 | |
SP3.4 | S111A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 45.0+/-1.2 | -5.93 | 4GG6 | 23063329 | |
SP3.4 | T113A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 12.5+/-0.6 | -6.69 | 4GG6 | 23063329 | |
SP3.4 | Y114A | B |
HLA-DQA1*03:01 HLA-DQB1*03:02 | WT | nan | EGSFQPSQE | WT | 15.6+/-0.7 | -6.56 | 4GG6 | 23063329 |