TCR name | TCR mutation | TCR mutation chain | MHC allele | MHC mutation | MHC mutation chain | Peptide | Peptide mutation | KD (μM) | ΔG (kcal mol-1) | PDB | Template PDB | PMID |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Hy.1B11 | WT | nan |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 14.3 +/- 1.5 | -6.61 | 3PL6 | 21199956 | |
Hy.1B11 | Y46A | B |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 15.8 +/- 0.9 | -6.55 | 3PL6 | 21199956 | |
Hy.1B11 | Q48A | B |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 108 +/- 4 | -5.41 | 3PL6 | 21199956 | |
Hy.1B11 | T50A | B |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 20 +/- 1.2 | -6.41 | 3PL6 | 21199956 | |
Hy.1B11 | D54A | B |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 30.8 +/- 2.6 | -6.15 | 3PL6 | 21199956 | |
Hy.1B11 | L95A | B |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 110 +/- 6 | -5.4 | 3PL6 | 21199956 | |
Hy.1B11 | F95A | A |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | >250 | \N | 3PL6 | 21199956 | |
Hy.1B11 | N97A | A |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 38 +/- 6 | -6.03 | 3PL6 | 21199956 | |
Hy.1B11 | E98A | A |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | >250 | \N | 3PL6 | 21199956 | |
Hy.1B11 | N31A | S52A | A | A |
HLA-DQA1*01:02 HLA-DQB1*05:01 | WT | nan | ENPVVHFFKNIVTPR | WT | 13.8 +/- 0.7 | -6.63 | 3PL6 | 21199956 |