TCR name | TCR mutation | TCR mutation chain | MHC allele | MHC mutation | MHC mutation chain | Peptide | Peptide mutation | KD (μM) | ΔG (kcal mol-1) | PDB | Template PDB | PMID |
---|---|---|---|---|---|---|---|---|---|---|---|---|
MS2-3C8 | WT | nan |
HLA-DRA*01:01 HLA-DRB1*04:01 | WT | nan | FSWGAEGQRPGFG | WT | 5.0+/- 0.1 | -7.23 | 3O6F | 21297580 | |
MS2-3C8 | T29A | A |
HLA-DRA*01:01 HLA-DRB1*04:01 | WT | nan | FSWGAEGQRPGFG | WT | 0.42+/- 0.02 | -8.7 | 3O6F | 21297580 | |
MS2-3C8 | K96A | A |
HLA-DRA*01:01 HLA-DRB1*04:01 | WT | nan | FSWGAEGQRPGFG | WT | 6.0+/- 0.1 | -7.12 | 3O6F | 21297580 | |
MS2-3C8 | E50A | B |
HLA-DRA*01:01 HLA-DRB1*04:01 | WT | nan | FSWGAEGQRPGFG | WT | 6.0+/- 0.1 | -7.12 | 3O6F | 21297580 | |
MS2-3C8 | T55A | B |
HLA-DRA*01:01 HLA-DRB1*04:01 | WT | nan | FSWGAEGQRPGFG | WT | 6.8+/- 0.1 | -7.05 | 3O6F | 21297580 | |
MS2-3C8 | S98A | B |
HLA-DRA*01:01 HLA-DRB1*04:01 | WT | nan | FSWGAEGQRPGFG | WT | >300 | \N | 3O6F | 21297580 | |
MS2-3C8 | N100A | B |
HLA-DRA*01:01 HLA-DRB1*04:01 | WT | nan | FSWGAEGQRPGFG | WT | >100 | \N | 3O6F | 21297580 |